Brain pathways that control dopamine release may influence motor control
The newly identified pathways appear to relay emotional information that helps to shape the motivation to take action.
A new framework to efficiently screen drugs
Novel method to scale phenotypic drug screening drastically reduces the number of input samples, costs, and labor required to execute a screen.
A new method makes high-resolution imaging more accessible
Labs that can’t afford expensive super-resolution microscopes could use a new expansion technique to image nanoscale structures inside cells.
The way sensory prediction changes under anesthesia tells us how conscious cognition works
A new study adds evidence that consciousness requires communication between sensory and cognitive regions of the brain’s cortex.
Cancer biologists discover a new mechanism for an old drug
Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.
3 Questions: What does innovation look like in the field of substance use disorder?
Hanna Adeyema and Carolina Haass-Koffler discuss the substance use disorder crisis and the future of innovation in the field.
A fast and flexible approach to help doctors annotate medical scans
“ScribblePrompt” is an interactive AI framework that can efficiently highlight anatomical structures across different medical scans, assisting medical workers to delineate regions of interest and abnormalities.
New open-source tool helps to detangle the brain
The software tool NeuroTrALE is designed to quickly and efficiently process large amounts of brain imaging data semi-automatically.
New method enables fast, accurate estimates of cardiovascular state to inform blood pressure management
A mathematical method, validated with experimental data, provides a fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.
Study across multiple brain regions discerns Alzheimer’s vulnerability and resilience factors
Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition.
AI model identifies certain breast tumor stages likely to progress to invasive cancer
The model could help clinicians assess breast cancer stage and ultimately help in reducing overtreatment.
Study reveals how an anesthesia drug induces unconsciousness
Propofol, a drug commonly used for general anesthesia, derails the brain’s normal balance between stability and excitability.
Implantable microphone could lead to fully internal cochlear implants
This tiny, biocompatible sensor may overcome one of the biggest hurdles that prevent the devices from being completely implanted.
Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution
Three innovations by an MIT-based team enable high-resolution, high-throughput imaging of human brain tissue at a full range of scales, and mapping connectivity of neurons at single-cell resolution.
Just thinking about a location activates mental maps in the brain
MIT neuroscientists have found that the brain uses the same cognitive representations whether navigating through space physically or mentally.