Topic
Genome
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Fast modeling of cancer mutations
New genome-editing technique enables rapid analysis of genes mutated in tumors.
October 22, 2014 -
Kellis to lead MIT team in new phase of GTEx project to elucidate basis of disease predisposition
NIH-sponsored work to characterize genetic variation in human tissues with roles in diabetes, heart disease, and cancer.
August 5, 2014 -
It’s in the genes — but whose?
Genetic material hitchhiking in our cells may shape physical traits more than we thought.
May 12, 2014 -
Broad Institute awarded first patent for CRISPR-Cas9 system
April 17, 2014 -
Research reveals structure of key CRISPR complex
Work reveals how a genome-editing tool works to correct errors in the genetic code.
February 13, 2014 -
Unusual suspects
Computer models plus observations of RNA inside a cell help scientists home in on a short list of interesting RNA ‘machines.’
December 15, 2013 -
Speeding up gene discovery
New gene-editing system enables large-scale studies of gene function.
December 12, 2013 -
Controlling genes with light
New technique can rapidly turn genes on and off, helping scientists better understand their function.
July 22, 2013 -
Research update: Genome editing becomes more accurate
Improved technique makes it easier to add or delete genes in living cells, with less risk of off-target DNA damage.
July 21, 2013 -
Reading DNA, backward and forward
MIT biologists reveal how cells control the direction in which the genome is read.
June 23, 2013 -
Cardiac development needs more than protein-coding genes
Biologists find that long non-coding RNA molecules are necessary to regulate differentiation of embryonic stem cells into cardiac cells.
January 24, 2013 -
Editing the genome with high precision
New method allows scientists to insert multiple genes in specific locations, delete defective genes.
January 3, 2013 -
Evolution: It’s all in how you splice it
MIT biologists find that alternative splicing of RNA rewires signaling in different tissues and may often contribute to species differences.
December 20, 2012 -
Researchers identify biochemical functions for most of the human genome
New map provides a reference for interpreting function of disease-associated regions.
September 5, 2012 -
Turning on key enzyme blocks tumor formation
Drug-like molecule restores normal cell metabolism, preventing cancer cells from growing.
August 27, 2012 -
Searching genomic data faster
Biologists’ capacity for generating genomic data is increasing more rapidly than computing power. A new algorithm will help them keep up.
July 10, 2012 -
Genetic 911: Cells’ emergency systems revealed
Study examines how cells exploit gene sequences to cope with toxic stress.
July 3, 2012 -
Getting to the root of genetics
Manolis Kellis uses computational techniques to decipher human disease.
April 17, 2012 -
Seeing cancer in three dimensions
Scientists find that the 3-D structure of a cancer cell’s chromosomes plays a big role in which genes get deleted or copied.
November 21, 2011 -
Materials research in the Information Age
MIT, Lawrence Berkeley launch new tool to calculate properties of new materials
November 4, 2011