To make mini-organs grow faster, give them a squeeze
Study finds that compressing cells, and crowding their contents, can coax them to grow and divide.
Alzheimer’s risk gene disrupts endocytosis, but another disease-linked gene could help
Astrocytes with the APOE4 gene variant show deficits of a key cellular function, but overexpressing the gene PICALM overcame the defect.
Nanoparticles can turn off genes in bone marrow cells
Using these new particles, researchers could develop treatments for heart disease and other conditions.
Neuroscientists discover a molecular mechanism that allows memories to form
Modifications to chromosomes in “engram” neurons control the encoding and retrieval of memories.
New gene regulation model provides insight into brain development
A well-known protein family binds to many more RNA sequences than previously thought in order to help neurons grow.
Scientists discover new rules about “runaway” transcription
Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.
Bringing RNA into genomics
ENCODE consortium identifies RNA sequences that are involved in regulating gene expression.
3 Questions: Seychelle Vos on detangling DNA
An unconventional geneticist uses cryogenic electron microscopy and crystallography to understand gene expression and cell fate.
HIV genome bends over backwards to help virus take over cells
Differently shaped RNA molecules allow HIV to express different genes from the same RNA sequence.
Historic migration patterns are written in Americans' DNA
Genetic, geographic, and demographic data from more than 30,000 Americans reveal more genetic diversity within ancestry groups than previously thought.
Gerald Fink awarded the Genetic Society of America’s Thomas Hunt Morgan Medal
Award recognizes scientists for lifetime achievement in genetics research who has a strong history as a mentor.
Maurice Fox, professor emeritus of biology, dies at 95
A caring mentor and staunch political activist, Fox cared deeply about his students, the department, and the scientific enterprise.
Genetic screen offers new drug targets for Huntington’s disease
Neuroscientists identify genes that modulate the disease’s toxic effects.
Putting a finger on the switch of a chronic parasite infection
Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention.
Whitehead Institute receives $10 million to study sex chromosomes’ impact on women’s health
Gift establishes the Brit Jepson d’Arbeloff Center on Women's Health.