A new study by MIT researchers finds that an experimental Alzheimer’s treatment involving sound and light stimulation at a frequency of 40 Hz is associated with, “an increase in activity of the brain's own cleanup crew; the glymphatic system,” reports Pandora Dewan for Newsweek. The findings offer an, “exciting, non-invasive potential treatment option for patients with neurological disorders in the future,” Dewan notes.
MIT scientists have found that an experimental treatment for Alzheimer's disease involving sounds and flickering lights appears to “ramp up the brain’s waste disposal networks, which boosts the clearance of beta-amyloid and other toxic proteins that contribute to memory and concentration problems,” reports Clare Wilson for New Scientist. “Once we understand the mechanism, we can probably figure out how to further optimize this whole concept and improve the efficacy,” explains Prof. Li-Huei Tsai.
Prof. Feng Zhang has been named to STAT’s 2024 STATUS List, which highlights the leaders shaping the future of health and life sciences, reports Dialynn Dwyer for Boston.com. “Among the companies he’s co-founded is Editas Medicine, which as of late 2023 was now the official holder of patent rights to the CRISPR-Cas9 gene editing tool used in the sickle cell therapy Casgevy, and Aera Therapeutics, which in February 2023 raised $193 million in venture funding to develop protein nanoparticles as a way of delivering gene editing,” Dwyer writes.
Senior lecturer Tara Swart speaks with Los Angeles Times reporter Deborah Netburn about healthy compartmentalization. Swart says “at its most useful, compartmentalization is the ability to acknowledge challenges in your personal circumstances or current events, and make a conscious decision to not allow those things to take over your thoughts and emotions,” writes Netburn. “But that doesn’t mean shutting out the world.”
MIT researchers have used machine learning to uncover the different kinds of sentences that most likely to activate the brain’s key language processing centers, reports Kyle Wiggers and Devin Coldewey for TechCrunch. The model, “was able to predict for novel sentences whether they would be taxing on human cognition or not,” they explain.
Researchers from MIT and elsewhere have developed a new AI technique for teaching robots to pack items into a limited space while adhering to a range of constraints, reports Nick Hilden for Scientific American. “We want to have a learning-based method to solve constraints quickly because learning-based [AI] will solve faster, compared to traditional methods,” says graduate student Zhutian “Skye” Yang.
MIT researchers have “used an algorithm to sort through millions of genomes to find new, rare types of CRISPR systems that could eventually be adapted into genome-editing tools,” writes Sara Reardon for Nature. “We are just amazed at the diversity of CRISPR systems,” says Prof. Feng Zhang. “Doing this analysis kind of allows us to kill two birds with one stone: both study biology and also potentially find useful things.”
Writing for CNBC, Senior Lecturer Tara Swart explains how an unexpected financial windfall can impact the brain. Swart says there, “are three remarkable things that happen to your brain when you unexpectedly receive a large sum of money overnight,” a dopamine deluge, the five stages of grief and a shift in perspective and social dynamics.
Prof. David Rand speaks with Wall Street Journal reporter Christopher Mims about the impact of generative AI on the spread of misinformation. “When you show people deepfakes and generative AI, a lot of times they come out of the experiment saying, ‘I just don’t trust anything anymore,’” says Rand.
Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li Huei Tsai, has developed a “specialized headset that delivers 40Hz auditory and visual stimulation” to the brain, which could potentially slow down the cognitive decline and neurodegeneration in Alzheimer’s disease, reports William A. Haseltine for Forbes. Prof. Li-Huei Tsai “and her team speculated that if gamma wave activity is reduced in Alzheimer’s disease, perhaps, artificially stimulating the brain may enhance synchronized firing and restore cognition,” writes Haseltine.
Researchers from MIT and Harvard have found that an adult’s ability to “parse the early attempts of children to talk may also help the children learn how to speak properly faster,” reports Jess Thomson for Newsweek. “These adult listening abilities might help children communicate very early and highlight that speech is a good way to share information with others," says postdoctoral associate Stephan Meylan. "That said, there is a lot of diversity in how adults and children interact across the world, both within and across different social and cultural contexts. This means that there are very likely many pathways to understanding language."
Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li-Huei Tsai, is using a 40 Hzlight-flickering and auditory headset to help slow the progression of Alzheimer’s and restore cognition, reports William A. Haseltine for Forbes. “A recent pilot clinical trial found that this technology is not only safe and tolerable for home use, but also has a positive impact on reducing symptoms associated with age-related neurodegeneration,” writes Haseltine.
Researchers at MIT and elsewhere have identified key cell types that may protect the brain against Alzheimer’s symptoms, reports Sara Reardon for Nature. “Most Alzheimer’s research has focused on excitatory neurons, which relay electrical signals to activate other neurons,” explains Reardon. “But the authors found that the cells with reelin or somatostatin were inhibitory neurons, which halt neuronal communication. These inhibitory cells might therefore have a previously unknown role in the types of cognitive function that are lost during Alzheimer’s.”
Sloan Senior Lecturer Tara Swart Bieber speaks with Newsweek reporter Pandora Dewan about exercises that can help improve memory. "Memory is something that can be trained using neuroplasticity, which is the brain's ability to be malleable throughout life," said Bieber.
Adjunct Prof. Tali Sharot speaks with NPR Life Kit host Marielle Segarra about how lying impacts the brain. Sharot refers to an experiment she conducted that used brain imaging technology to monitor how the brain reacts to lying and found that as adults “grew more comfortable lying, the emotional response decreased – meaning that the players became more and more desensitized to their dishonesty with each subsequent lie.”