Unlocking mRNA’s cancer-fighting potential
MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and powerful treatments.
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Hitchhiking cancer vaccine makes progress in the clinic
MIT spinout Elicio developed a vaccine based on a lymph node-targeting approach first developed at the Koch Institute. Phase 1 solid tumor clinical trial results are promising so far.
Immune action at a distance
MIT and MGH researchers design a local, gel-based drug-delivery platform that may provoke a system-wide immune response to metastatic tumors.
A snapshot of cancer vaccine development
The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.
Vaccine delivers a boost to T cell therapy
The new strategy may enable engineered T cells to eradicate solid tumors such as glioblastoma.
Gamifying medical data labeling to advance AI
MIT alumnus’ platform taps the wisdom of crowds to label medical data for AI companies.
Putting the STING into cancer immunotherapy
A cancer vaccine combining checkpoint blockade therapy and a STING-activating drug eliminates tumors and prevents recurrence in mice.
A traveler on bioengineering’s many paths
Immunology research, public health service, and student leadership are all part of senior Julian Zulueta’s journey toward becoming a physician-scientist.
Why lung cancer doesn’t respond well to immunotherapy
A new study reveals that lymph nodes near the lungs create an environment that weakens T-cell responses to tumors.
How different cancer cells respond to drug-delivering nanoparticles
The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer.
Startup lets doctors classify skin conditions with the snap of a picture
Piction Health, founded by Susan Conover SM ’15, uses machine learning to help physicians identify and manage skin disease.
New model helps identify mutations that drive cancer
The system rapidly scans the genome of cancer cells, could help researchers find targets for new drugs.
A stealthy way to combat tumors
MIT biologists show that helper immune cells disguised as cancer cells can help rejuvenate T cells that attack tumors.
Modeling the mechanisms of metastasis
Collaborative team wins prestigious NIH grant to investigate the physical forces that influence metastatic cancer.
Engineers devise a way to selectively turn on RNA therapies in human cells
A new RNA-based control switch could be used to trigger production of therapeutic proteins to treat cancer or other diseases.