New conversation on sociotechnical systems

On April 30, Li-Huei Tsai will discuss a potential memory-based treatment for PTSD

Press Contact

Jacqueline Paris
Phone: 617-253-0477
Sociotechnical Systems Research Center (SSRC)

The MIT Sociotechnical Systems Research Center invites you to its next spring seminar in the "Conversations on Sociotechnical Systems" series on Wed., April 30, from 4:15-5:30 p.m. in Building E38-615. Light refreshments will be served.

Traumatic events generate some of our most enduring memories. The most efficacious treatments to diminish recent traumata capitalize on memory-updating mechanisms during reconsolidation, which are initiated upon memory recall. In mice, reconsolidation-updating models that successfully modified recent memories failed to diminish remote ones. This seminar will illustrate how the chromatin enzyme histone deacetylase 2 (HDAC2) affects synaptic plasticity and memory formation in mice. It will explain how histone deacetylase inhibitors inhibitors can make both recent and remote memories more malleable to change — and may therefore constitute a treatment option for post-traumatic stress disorder.

Li-Huei Tsai, director of MIT's Picower Institute for Learning and Memory, will present “The Role of Epigenetics-Mediated Gene Expression in Memory Reconsolidation.”

Topics: Special events and guest speakers, Post-traumatic stress disorder (PTSD), Memory, Picower Institute for Learning and Memory, Sociotechnical Systems Research Center


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